## Latest Publications

### Submitted to ESMO RWD 2026

**Development and Validation of an Agentic AI-Augmented Living Decision Support Tool for Oncology: A Breast Cancer Pilot Study**  
Rugo H, Forsythe A, Flora D, et al. (2026). Development and validation of an agentic AI-augmented living decision support tool for oncology: A breast cancer pilot study. _ESMO Real World Data Digital Oncol._  
Manuscript submitted

### SABCS 2025

**Development and Validation of a Living Decision Support Tool (Living-DST) in Oncology Using Agentic AI-Augmented Systematic Literature Review (SLR)**  
Schwartzberg L, Forsythe A, Flora D, et al. Development and validation of a living decision support tool in oncology using agentic AI-augmented systematic literature review \[abstract PS3-04-10\]. _Clin Cancer Res._ 2026;32(4 Suppl):PS3-04-10. doi:10.1158/1557-3265.SABCS25-PS3-04-10  
[See Publication](https://aacrjournals.org/clincancerres/article/32/4_Supplement/PS3-04-10/772812)

### ESMO AI 2025

**Development and Validation of a Living Decision Support Tool (Living-DST) in Non-Small Cell Lung Cancer (NSCLC) Using Agentic AI-Augmented Systematic Literature Review (SLR)**  
Borghaei H, Forsythe A, Rege J, Liu R, Reck M. Development and validation of a living decision support tool (Living-DST) in non-small cell lung cancer (NSCLC) using agentic AI-augmented systematic literature review (SLR) \[abstract 281P\]. _Ann Oncol._ 2025;36(10 suppl):1-153. 10.1016/esmorw/esmorw100199  
[See Publication](https://oncologypro.esmo.org/congress-resources/esmo-ai-digital-oncology-congress-2025?presentation=development_and_validation_of_a_living_decision_su)

### WCLC 2025

**Living Systematic Review Linked to Guidelines and Regulatory Approvals as a Treatment Decision Support Tool in NSCLC**  
Borghaei H, Forsythe A, Grieve S, Liu R, Rege JM, Sarkisian S. Living systematic review linked to guidelines and regulatory approvals as a treatment decision support tool in NSCLC \[abstract P1.17.78\]. _J Thorac Oncol_. 2025;20(10 S1):S250-S251. doi:10.1016/j.jtho.2025.09.463  
[See Publication](https://doi.org/10.1016/j.jtho.2025.09.463)

### ASCO Annual 2025

**Comprehensive decision support tool (DST) in breast cancer: Automated National Comprehensive Cancer Network (NCCN) guidelines linked to living systematic literature review (SLR)**  
Kaufman PA, Forsythe A, Liu R, Rege J, Cortes J. Comprehensive decision support tool (DST) in breast cancer: automated National Comprehensive Cancer Network (NCCN) guidelines linked to living systematic literature review (SLR) \[abstract\]. _J Clin Oncol_. 2025;43:e13676. doi:10.1200/JCO.2025.43.16_suppl.e13676  
[See Publication](https://doi.org/10.1200/JCO.2025.43.16_suppl.e13676)

### ASCO Annual 2025

**A living systematic literature review (L-SLR) for non–small-cell lung (NSCLC), prostate (PC), and breast cancer (BC), built with an agentic text annotation system powered by large language models (LLM) to assist treatment decision making**  
Sarkisian S, Liu RJ, Liu E, Forsythe A. A living systematic literature review (L-SLR) for non–small-cell lung (NSCLC), prostate (PC), and breast cancer (BC), built with an agentic text annotation system powered by large language models (LLM) to assist treatment decision making \[abstract\]. _J Clin Oncol_. 2025;43:e13677. doi:10.1200/JCO.2025.43.16_suppl.e1365  
[See Publication](https://doi.org/10.1200/JCO.2025.43.16_suppl.e13657)

### NCCN Annual 2025

**Real-Time Clinical Trial Data Library in Non-Small Cell Lung (NSCLC), Prostate (PC), and Breast Cancer (BC) to Support Informed Treatment Decisions: Now a Reality With a Fine-Tuned Large Language Model (LLM)**  
Liu RJ, Forsythe A, Rege JM, Kaufman PA. Real-time clinical trial data library in non-small cell lung (NSCLC), prostate (PC), and breast cancer (BC) to support informed treatment decisions: now a reality with a fine-tuned large language model (LLM) \[abstract\]. _J Natl Compr Canc Netw._ 2025;23(3.5):BIO25-024. doi: 10.6004/jnccn.2024.7156  
[See Publication](https://doi.org/10.6004/jnccn.2024.7156)

## More publications by Oncoscope-AI leadership

01. **Liu R, Mosselman JJ, Hanegraaf P, van der Schans J, Rizzo M, Forsythe A.** SA24 Can an Integrated Systematic Literature Review (SLR) Database Improve the Speed of Title and Abstract (TIAB) Review? A Case Study Using Multiple Myeloma (MM) Projects in Interventional and Real-World Evidence (RWE) Evidence. _Value in Health._ 2023;27(12):S545. DOI: [10.1016/j.jval.2023.09.2933](https://doi.org/10.1016/j.jval.2023.09.2933)

02. **Liu J, Buer A, Rizzo M, Sarri G, Forsythe A.** HTA63 The Data Lifecycle: Towards a Standardized Relational Data Model to Support Living Systematic Literature Reviews? – Use Case Demonstration with LiveSLR®. _Value in Health._ 2023;26(6):S270. DOI: [10.1016/j.jval.2023.03.1492](https://doi.org/10.1016/j.jval.2023.03.1492)

03. **Liu J, Jafar R, Girard LA, Thorlund K, Forsythe A.** MSR8 Update on the LIVESTART™ Artificial Intelligence (AI) Systematic Literature Review (SLR) Tool – Can It Aid in Limited Data Extraction for LIVEREF™? _Value in Health._ 2023;26(6):S279. DOI: [10.1016/j.jval.2023.03.1544](https://doi.org/10.1016/j.jval.2023.03.1544)

04. **Liu J, Jafar R, Girard LA, Thorlund K, Forsythe A.** MSR33 Re-Training of the Artificial Intelligence (AI) Tool LIVESTART™ with Additional Datasets: Updated Accuracy in the Title and Abstract Review Stage of Systematic Literature Reviews (SLR). _Value in Health._ 2023;26(6):S283-S284. DOI: [10.1016/j.jval.2023.03.1569](https://doi.org/10.1016/j.jval.2023.03.1569)

05. **He C, Ammann E, Forsythe A.** CO141 Using LiveSLR platform to evaluate the impact of Duration of Treatment (DOT) on Progression Free Survival (PFS) in Multiple Myeloma (MM). _Value in Health._ 2022;25(12):S45. DOI: [10.1016/j.jval.2022.09.218](https://doi.org/10.1016/j.jval.2022.09.218)

06. **Liu J, Verhoek A, Thorlund K, Heeg B, Sarri G, Forsythe A.** HTA35 Should Health Technology Assessment (HTA) Bodies Utilize Living HTA Tools? Validation of LiveSLR® and LiveNMA™ Tools Using ICER’S Class Review in Relapsed Refractory Multiple Myeloma (RRMM). _Value in Health._ 2022;25(12):S302-S303. DOI: [10.1016/j.jval.2022.09.1495](https://doi.org/10.1016/j.jval.2022.09.1495)

07. **Egunsola O, Verhoek A, Liu J, Thorlund K, Heeg B, Kwon C, Forsythe A.** HTA145 Living Network Meta-Analysis for Up-to-Date Comparative Effectiveness: A Case Study in Multiple Myeloma Maintenance. _Value in Health._ 2022;25(12):S325. DOI: [10.1016/j.jval.2022.09.1603](https://doi.org/10.1016/j.jval.2022.09.1603)

08. **He C, Chen Z, Kwon C, Musat M, Liu J, Sarri G, Forsythe A.** HTA199 The Reality of Living Systematic Literature Reviews (SLRs) to Support Timely Healthcare Decisions: A Case Study in Relapsed/Refractory Multiple Myeloma. _Value in Health._ 2022;25(12):S335. DOI: [10.1016/j.jval.2022.09.1657](https://doi.org/10.1016/j.jval.2022.09.1657)

09. **Liu J, Jafar R, Girard LA, Thorlund K, Forsythe A.** MSR74 Can Artificial Intelligence (AI) Replace a Human Reviewer in Systematic Literature Review (SLR)? Validation of LIVESTART™ Tool. _Value in Health._ 2022;25(12):S364. DOI: [10.1016/j.jval.2022.09.1805](https://doi.org/10.1016/j.jval.2022.09.1805)

10. **Moreau A, Richard ME, Harricharan S, Forsythe A.** POSC421 Understanding the Impact of Congress Abstracts on Overall Publications in Multiple Myeloma (MM) – Results of a Systematic Literature Review (SLR). _Value in Health._ 2022;25(1):S275-S276. DOI: [10.1016/j.jval.2021.11.1341](https://doi.org/10.1016/j.jval.2021.11.1341)

11. **Moreau A, Richard ME, Harricharan S, Forsythe A.** POSC422 The Impact of Congress Abstracts on Overall Publications in Acute Myeloid Leukemia (AML): Results of a Systematic Literature Review. _Value in Health._ 2022;25(1):S276. DOI: [10.1016/j.jval.2021.11.1342](https://doi.org/10.1016/j.jval.2021.11.1342)

12. **Richard ME, Harricharan S, Forsythe A.** PCN291 Always up-to-Date Systematic Literature Reviews (SLRS) NOW a Reality – an Example in NEWLY Diagnosed ACUTE Myeloid Leukemia (ND AML) and Relapsed/Refractory ACUTE Lymphoblastic Leukemia (RR ALL). _Value in Health._ 2020;23(Suppl2):S473. DOI: [10.1016/j.jval.2020.08.428](https://doi.org/10.1016/j.jval.2020.08.428)

13. **Hearnden J, Dudoit K, Kim E, Tremblay G, Forsythe A.** PMU118 Use of computer-assisted methods to realize the concept of a living systematic review via an online platform. _Value in Health._ 2019;22(Suppl3):S729. DOI: [10.1016/j.jval.2019.09.1736](https://doi.org/10.1016/j.jval.2019.09.1736)

14. **Forsythe A, Hearnden J, Dudoit K, Crotty C, Tremblay G.** PCN243 Real-time systematic literature reviews (SLR) – Dream or reality with computer-assisted methods: A case study in acute myeloid leukemia (AML). _Value in Health._ 2019;22(Suppl2):S102. DOI: [10.1016/j.jval.2019.04.364](https://doi.org/10.1016/j.jval.2019.04.364)